With the patented BioCell® Collagen formula, Modere has helped make collagen a vital part of mainstream discussions about health and wellness.
In addition to its progressive efforts, the company has built a strong reputation among its customers, generating positive word-of-mouth and glowing reviews. Now, consumers know that if they want to support skin hydration, joint function, and overall mobility, Modere is the company to turn to.
For years, BioCell was the best collagen for women and men who longed for noticeable anti-aging results without resorting to invasive procedures or synthetic ingredients.
However, in April 2025, everything changed. Modere shut its doors, closing down and dismaying many loyal customers. Once you’ve become reliant on a product for its benefits to your health and wellness routines, it can be challenging to readjust to life without it. To this end, in the wake of Modere’s closure, many have been desperately searching for a proper replacement. The collagen supplement market at large has been left in a state of flux.
Fortunately, the solution to these concerns may lie in the next generation of collagen formulations. These new formulas extend beyond beauty to support metabolic health, cognitive clarity, and digestive balance in ways that earlier collagen supplements could not.
Collagen B3 from Sisel International is an effective example of this new breed. CollagenB3 is a science-supported blend whose innovation indicates where the collagen category is headed. While BioCell laid the foundation for these breakthroughs, today’s wellness community demands more from their supplements, and brands like Sisel International are rising to the challenge.
Modere and BioCell: Setting the Benchmark
Modere’s BioCell Collagen was the gold standard in collagen supplements for several years. The formula addressed multiple signs of aging, such as skin dryness, joint stiffness, and a decline in elasticity. Through its effectiveness at combating these symptoms, not only did it work wonders for countless customers, but it also realigned the larger narrative surrounding collagen supplements.
By combining hydrolyzed Type II collagen with hyaluronic acid and chondroitin sulfate, Modere’s BioCell demonstrated what a difference such products could make. As a result, it quickly became a trusted favorite, especially among women seeking the best collagen for skin, hair, and nails without compromising ingredient integrity.
Furthermore, in addition to the bona fides of the product itself, Modere’s unique approach to direct selling cut through the noise of the market and elevated the brand. With a clean aesthetic, influencer-friendly packaging, and social media-savvy outreach, BioCell attracted younger demographics and wellness enthusiasts who might have previously avoided MLMs. Through these methods, Modere redefined how a direct sales brand could succeed in the modern age.
Despite the company’s formative product legacy and boundary-pushing marketing approach, Modere couldn’t help but succumb to larger business challenges. Though specifics regarding the closure are scarce, they serve as a warning sign for others in the industry. As consumer expectations continue to become more nuanced and advanced, companies must be adept at innovating in branding and formulation. As the situation stabilizes, the critical question is who will succeed BioCell and who will drive collagen innovation forward in the coming decade.
The Market Shift: What Today’s Consumers Want From Collagen
Following Modere’s departure, the collagen supplement market is changing quickly. Modern wellness-focused consumers are not merely interested in superficial perks such as smoother skin or shinier hair. Instead, they seek products that offer comprehensive support for the whole body, from the brain to the bones. Collagen is now recognized as more than a simplistic beauty enhancer; it is viewed as a vital protein contributing to skin health, joint flexibility, cognitive performance, and even metabolic equilibrium.
Additionally, the growing preference for clean ingredients, science-forward formulations, and functional blends clarifies why outdated products are losing popularity. Shoppers are focusing on brands that prioritize innovation and transparency, particularly those offering collagen supplements with added benefits like MCT oil for cognitive support or hyaluronic acid for skin hydration.
Sisel’s Answer: CollagenB3 as the New Standard
Enter CollagenB3™ by Sisel International, a comprehensive collagen supplement engineered for the next generation of wellness seekers. Unlike many single-source formulas, CollagenB3 blends three types of collagen (Types I, II, and III) with a potent mix of functional ingredients that amplify its benefits across multiple systems in the body.
- Type I and III Collagen are foundational for healthy skin, strong nails, and resilient hair.
- Type II Collagen supports joint flexibility and cartilage strength.
- Hyaluronic Acid adds hydration, plumping the skin and reducing the appearance of fine lines.
- MCT Oil acts as brain fuel, promoting mental clarity and sustained energy—an uncommon but highly desirable benefit in a collagen product.
- Chaga, Cordyceps, Biotin, and L-Tryptophan support immune function, stress relief, and mood balance, making this formula a true mind-body solution.
CollagenB3 stands out not only for its diverse ingredients but also for its effectiveness and clarity surrounding it. Unlike many well-known collagen products that offer only 3–7 grams per serving and obscure their actual compositions behind proprietary blends (as in the case of BioCell), CollagenB3 provides over 20 grams of collagen per serving. This translates to genuine, adequate amounts aimed at producing visible results.
Sisel’s internal manufacturing process guarantees quality supervision at all levels, and the formula reflects the brand’s enduring dedication to clean, effective, and toxin-free products. As consumer expectations evolve toward multifunctional nutrition, CollagenB3 addresses the gap left by BioCell and enhances the entire category.
Direct Sales Done Right: Sisel vs. Other MLM Models
Sisel offers what is widely considered one of the most lucrative compensation plans in the industry. With up to eight profit centers and higher payouts than many legacy companies, Sisel empowers its distributors in ways that Modere and others often fall short of.
While some companies push rapid recruitment with minimal support, Sisel focuses on long-term success through education, mentorship, and genuine product belief. The company’s four-year streak of consistent sales growth—culminating in a 94.4% increase from 2021 to 2024—speaks volumes about its sustainable momentum.
Sisel’s commitment to clean science, ethical practices, and distributor support reflects what today’s consumers and entrepreneurs seek in a direct sales partner. The closure of Modere serves as a cautionary tale, but Sisel’s steady rise illustrates how thoughtful business strategies and innovations can create a lasting impact.
The Future of Collagen Is Here
Modere helped bring collagen into the spotlight, but the spotlight has since widened. Today’s consumers are looking beyond single-function supplements toward smart, synergistic solutions that deliver more for their money and health. As BioCell exits the market with Modere’s closure, the door is open for a new generation of wellness-focused formulas to take its place.
Sisel’s CollagenB3 excels as an impressive successor crafted for future needs. Merging multi-source collagen with MCT oil, hyaluronic acid, and selected botanicals enhances skin elasticity, joint health, and cognitive clarity in a clean, science-driven formulation. This blend embodies the market’s direction and explains why discerning consumers are transitioning.
For those contemplating options after BioCell, the solution is not merely about product replacement; it’s an upgrade to a more intelligent strategy. The next phase of collagen innovation has already arrived and is tailored for beauty, body, and brain.
