However, in April 2025, everything changed. Modere shut its doors, closing down and dismaying many loyal customers. Once you’ve become reliant on a product for its benefits to your health and wellness routines, it can be challenging to readjust to life without it. To this end, in the wake of Modere’s closure, many have been desperately searching for a proper replacement. The collagen supplement market at large has been left in a state of flux.
Fortunately, the solution to these concerns may lie in the next generation of collagen formulations. These new formulas extend beyond beauty to support metabolic health, cognitive clarity, and digestive balance in ways that earlier collagen supplements could not.
Collagen B3 from Sisel International is an effective example of this new breed. CollagenB3 is a science-supported blend whose innovation indicates where the collagen category is headed. While BioCell laid the foundation for these breakthroughs, today’s wellness community demands more from their supplements, and brands like Sisel International are rising to the challenge.
Modere and BioCell: Setting the Benchmark
Modere’s BioCell Collagen was the gold standard in collagen supplements for several years. The formula addressed multiple signs of aging, such as skin dryness, joint stiffness, and a decline in elasticity. Through its effectiveness at combating these symptoms, not only did it work wonders for countless customers, but it also realigned the larger narrative surrounding collagen supplements. By combining hydrolyzed Type II collagen with hyaluronic acid and chondroitin sulfate, Modere’s BioCell demonstrated what a difference such products could make. As a result, it quickly became a trusted favorite, especially among women seeking the best collagen for skin, hair, and nails without compromising ingredient integrity. Furthermore, in addition to the bona fides of the product itself, Modere’s unique approach to direct selling cut through the noise of the market and elevated the brand. With a clean aesthetic, influencer-friendly packaging, and social media-savvy outreach, BioCell attracted younger demographics and wellness enthusiasts who might have previously avoided MLMs. Through these methods, Modere redefined how a direct sales brand could succeed in the modern age. Despite the company’s formative product legacy and boundary-pushing marketing approach, Modere couldn’t help but succumb to larger business challenges. Though specifics regarding the closure are scarce, they serve as a warning sign for others in the industry. As consumer expectations continue to become more nuanced and advanced, companies must be adept at innovating in branding and formulation. As the situation stabilizes, the critical question is who will succeed BioCell and who will drive collagen innovation forward in the coming decade.The Market Shift: What Today’s Consumers Want From Collagen
Following Modere’s departure, the collagen supplement market is changing quickly. Modern wellness-focused consumers are not merely interested in superficial perks such as smoother skin or shinier hair. Instead, they seek products that offer comprehensive support for the whole body, from the brain to the bones. Collagen is now recognized as more than a simplistic beauty enhancer; it is viewed as a vital protein contributing to skin health, joint flexibility, cognitive performance, and even metabolic equilibrium. Additionally, the growing preference for clean ingredients, science-forward formulations, and functional blends clarifies why outdated products are losing popularity. Shoppers are focusing on brands that prioritize innovation and transparency, particularly those offering collagen supplements with added benefits like MCT oil for cognitive support or hyaluronic acid for skin hydration.Sisel’s Answer: CollagenB3 as the New Standard
Enter CollagenB3™ by Sisel International, a comprehensive collagen supplement engineered for the next generation of wellness seekers. Unlike many single-source formulas, CollagenB3 blends three types of collagen (Types I, II, and III) with a potent mix of functional ingredients that amplify its benefits across multiple systems in the body.- Type I and III Collagen are foundational for healthy skin, strong nails, and resilient hair.
- Type II Collagen supports joint flexibility and cartilage strength.
- Hyaluronic Acid adds hydration, plumping the skin and reducing the appearance of fine lines.
- MCT Oil acts as brain fuel, promoting mental clarity and sustained energy—an uncommon but highly desirable benefit in a collagen product.
- Chaga, Cordyceps, Biotin, and L-Tryptophan support immune function, stress relief, and mood balance, making this formula a true mind-body solution.
